MTHFR (C677T) polymorphism and PR (PROGINS) mutation as genetic factors for preterm delivery, fetal death and low birth weight: A Northeast Indian population based study

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MTHFR (C677T) polymorphism and PR (PROGINS) mutation as genetic factors for preterm delivery, fetal death and low birth weight: A Northeast Indian population based study

UNLABELLED Preterm delivery (PTD) is one of the most significant contributors to neonatal mortality, morbidity, and long-term adverse consequences for health; with highest prevalence reported from India. The incidence of PTD is alarmingly very high in Northeast India. The objective of the present study is to evaluate the associative role of MTHFR gene polymorphism and progesterone receptor (PR)...

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Maternal Periodontal Disease as a Potential Risk Factor for Preterm Birth and Low Birth Weight

Background and Aim: Periodontal disease may cause adverse pregnancy outcomes such as low birth weight (LBW) or preterm birth (PTB). In the present study, mothers with one of these two delivery complications were analyzed regarding presence/absence of periodontal disease as a possible risk factor in comparison with related medical risk factors.   Materials and Methods: In this cross-sectiona...

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Factors associated with preterm delivery and low birth weight: a

Although preterm delivery and low birth weight (LBW) have been Background: studied in India, findings may not be generalisable to rural areas such as the Marathwada region of Maharashtra state. There is limited information available on maternal and child health indicators from this region. We aimed to present some local estimates of preterm delivery and LBW in the Osmanabad district of Marathwa...

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Does MTHFR C677T polymorphism predispose asthma? A North Indian study

Background: Involvement of impaired folate metabolism has been hypothesized to be a potential risk factor for the predisposition of asthma. The reports are conflicting on the potential association between atopic disease and polymorphism of the methylene-tetrahydrofolate reductase (MTHFR)-gene. Objective: We designed the study to investigate the association of C677T polymorphism of the MTHFR gen...

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ژورنال

عنوان ژورنال: Meta Gene

سال: 2015

ISSN: 2214-5400

DOI: 10.1016/j.mgene.2014.12.002